According to recent scientific research published in Proceedings of the National Academy of Sciences, a primitive version of DNA’s sister molecule, RNA, was where evolution of life began billions of years ago.
RNA is like DNA, except it doesn’t come in the iconic double-helix shape. It is still structurally similar, despite the fact that one of its four fundamental molecules, thymine, is replaced by uracil. Scientists have long believed that RNA was the key for life to begin flourishing on Earth.
But a discovery made by accident by Harvard researchers suggests this flourishing was caused by a slightly different make-up of the RNA molecule. Specifically, they believe that inosine may have replaced guanine in the RNA, which would have facilitated the development of lifeforms.
The change to the base nucleotides that make up DNA and RNA is the first possible evidence we have supporting the “RNA World Hypothesis,” which posits that RNA was essential to the development of the most primitive microbes.
Inosine was a surrogate for the RNA, according to Harvard University’s Professor Jack Szostak and graduate student Seohyun Kim. “Our study suggests that the earliest life forms of life (with A, U, C, and I) may have arisen from a different set of nucleobases than those found in modern life (A, U, C, and G),” Kim said.
When attempts were made in the laboratory to recreate adenine and guanine in DNA and RNA with the materials believed to have existed on primordial Earth, they failed. The nucleotides adenine and guanine are based on purine and bond with thymine/uracil and cytosine, respectively.
Too many undesired by-products were produced in the chemical reaction, causing issues. With inosine, however, the RNA was able to replicate quickly and with few errors, which are characteristics necessary for reproduction of the molecule to take place.
According to the research, this “turns out to exhibit reasonable rates and fidelities in RNA copying reactions. We propose that inosine could have served as a surrogate for guanosine in the early emergence of life.”
This discovery could substantiate the RNA World Hypothesis, in time possibly confirming RNA’s role in explaining where we came from.
In addition, this could help scientists identify which other planets have the essential components needed for life to exist.
She Adopted A Puppy – But Months Later It Looks Like This
It was Yumna Salooje’s big dream to adopt a little pet. As soon as she saw this adorable Alaskan malamute dog, she felt like she couldn’t go home without him. But after just a few months, Salooje started to notice something she really hadn’t expected…
When Yumna was looking to adopt a pet, she wasn’t particularly picky. She lived in South Africa, and all she wanted was a furry friend! However, a few months in, something unexpected happened.
New Family Member
Considering the fact that Yumna had been dreaming about having a pet for a long time, she decided to go for it. Aside from getting a pet, she was also ready for the responsibility that came with it. She was prepared to accept the challenge of caring for an animal. The catch here is, she had no idea what was coming when she adopted this puppy. Regardless of the potential difficulties, Yumna went for it, and it turned out to be worth it!
Bringing Him Home
After weeks of waiting for the most important day, Yumna finally got to take him home! She mentioned that he already grew a little bit by the time she saw him again, so the name she decided to give him was “Tydus”. The name, literally, means “great warrior”, and Yumna decided that he was just destined for something awesome. The little pooch was incredibly loving from day one, but Yumna had no idea what was coming.
As soon as Tydus came home, he was given a million toys, a comfortable bed, lots of food and even more love and attention! He had more space at home than he could ever imagine using, and this little king was settling in nicely. Yumna loved playing with her new puppy, and he was so incredibly active that it was hard to keep up with him at all times. All of Yumna’s friends loved playing with her new pet.
Below, this little puppy is pictured at eight weeks old, and he already looks like he’s getting much bigger. As he discovered his favorite toys, games, and better things to eat, he also started playing soccer. Little Tydus was growing up faster than Yumna had imagined, which triggered her curiosity in terms of how big he’ll actually become. However, she was too overwhelmed with love to think about that just yet.
Yumna not only flooded the puppy with toys and love, she also allowed him to play in the pool as well. She wanted him to get used to playing in the water and get acclimated with the pool scene in general. After all, puppies should love playing in the water! As soon as Tydus got close to the pool, he was a natural. He knew how to get the perfect shot by the pool, as well as actually swimming. It really looks like he was having a great time playing by the swimming pool.
Part Of The Family
It wasn’t long until Yumna was everyone’s favorite in the Saloojee family. He was becoming more loving and adorable with each and every day, and the puppy seemed to have endless reserves of energy. His favorite thing to do was play with all of Yumna’s siblings, as well as parents. However, Tydus was starting to look a little different, as well as doing things differently. He was already much bigger than most dogs his age…
Growing Too Fast
Every dog lover knows that puppies grow super quickly over time. Because every dog owner knows this fact, Yumna did not see anything strange about Tydus’s rapid growth. From the moment Yumna took Tydus into her home, she knew Tydus would grow to be a fairly large dog. Most Alaskan Malamutes, Tydus’s dog breed, are known to be pretty big. However, Tydus started to exhibit some odd characteristics. You’ll need to see this for yourself.
A Surprising Growth Spurt
No one realized at this point, but Tydus started to grow much more rapidly than all other dogs normally do. Every single day Tydus’s growth would jump off the charts. He started to reach his full grown size as a puppy. Yumna was so obsessed and in love with her new baby puppy that she would have adored him no matter what size he was. However, nobody knew just how big he was going to get. It was only a matter of time.
Before anyone realized anything was wrong, Tydus was already living up to his perfect name, ‘The Great Giant Warrier’. Tydus was growing exponentially, and before everyone’s eyes, Tydus reached the size of a full grown dog. Technically he was till a ‘puppy’ but Tydus already weighed 120 lbs (54 kilograms). For those who don’t know, that weight is enormous for an Alaskan Malamute. Anyone who met Tydus as a baby would not have ever recognized him!
Puppy Or Bear?
Pretty soon as Tydus grew and grew, he started to look more like a huge bear than a puppy. Even though he looked like a grown boy, he was still acting like puppy. His behavior reflected his true age. Yumna started to get a little nervous. She loved her dog more than life, but she started to worry if she could properly take care of an animal that large. At this point, Tydus was already towering over Yumna!
The Best Hugger
Tydus was never shy about giving love. He was the sweetest animal and loved to cuddle and give lots of hugs. He loved to jump all over Yumna. There was only one issue, his giant size made him a lot to handle. He was huge and fluffy. Hugging Tydus was full experience. Once Tydus reached two years old, he was gigantic. Owner Yumna opened up in Get Leashed magazine and stated, “To be honest, his size comes from all that magical fluff.”
Larger Than Life
Tydus was the greatest cuddle buddy in the whole world. He loved cuddling so much that he would even smile during a serious cuddle session. There was one hilarious problem. Tydus did not realize how big he was. This sweet puppy still believed he was a lap dog even though he couldn’t fit on Yumna’s lap. Even though Yumna and her family were used to Tydus height and weight, strangers started to stare.
Normal walks with Tydus quickly turned into crazy outings. People reacted with shock to Tydus’s large figure. Yumna even shared her experience with the Dodo and said, “His fluffiness is the first thing that catches attention, then his size.” She continued, “Wherever we go, even just for a walk around the block, we get stopped and asked about his size, age and most often, ‘What breed is he?’ I guess it’s not often that you see a lion-dog walking the street.”
When Fame Hit
After a short period of time, people took notice of Tydus and he became a social media star. Fame hit and there was no turning back. Luckily, Yumna couldn’t wait to share her beautiful dog with the world. The owner started her own instagram of her baby. Every day she would post photos of her adorable Alaskan Malamute. She wanted to show how well behaved and sweet he was. All of the sudden, Yumna had 140,000 followers. She said, “If his looks didn’t get your attention, his personality definitely will. He has an amazing soul that earns everyone’s affection.”
Robin To His Batman
Tydus might be the main event on his Instagram page, but he is far from the only star. He makes sure to share the spotlight with Trez, his brother, a Congo African Grey Parrot. The Instagram account is titled ‘Trez & Tydus.’ Trez happily joins his brother in goofy yet adorable photos together. Due to the way that Trez mimics everyone, Yumna likes to call him ‘The Ruler of Everything’ based on his very regal disposition.
Like most dogs, Tydus does not care for being serious. He always wants to play around and get into goofball activities. While it might be fun for Tydus and Yumna, it is less fun for stuffed animals such as this Mickey Mouse. Tydus is elated with sticking his teeth into his plush cotton center. All Mickey can do is lay there motionless and watch Tydus go to town on his insides. Yumna always ensures that Tydus has something to keep himself entertained.
Reach For The Sky
Tydus does not mess around when it comes to his toys. He takes them very seriously and makes sure to enjoy himself to the fullest when he is with them. His favorites have always been his plush purple dinosaur and his toy weapon. Perhaps he likes to entice the dinosaur into games of cops and robbers. We would bet the house that Tydus likely wins those battles. Due to his past decimation of Mickey, we are unsure if he is the cop or the robber…
Yumna is happy to share the joys of Tydus with her friends and Tydus is happy to tag along. He is always down for a road trip. Everywhere he goes he seems to be a star and the attention has certainly gotten to his head. Look at that attitude as he sits in the passenger seat with his shades on. His incognito eyewear is doing nothing to disguise him from his fans.
A Perfect Family
With Trez and Tydus by her side, Yumna has quite the adorable and playful family. They are always posing for photos together that make their Instagram followers go crazy. In this one, Tydus doesn’t seem pleased with Yumna and Trez stealing his spotlight. He feels the best way to take back the attention is a slight gnaw on Yumna’s arm. She is always capturing shots like this and who could blame her. Tydus is too cute not to photograph.
As much as Yumna loves to play around with Tydus, it is not always the fair fight that it seems to be. Due to Tydus’s size, he can easily overpower her when they are fooling around. Tydus does not exactly know his own strength but that does not keep Yumna from playing with her beautiful dog. In comparison, Tydus does not look so small next to his mother. They always have too good of a time together.
Since Tydus is near the size of a small human, he might as well help out his mother with human tasks. Yumna is happy to have Tydus help her with administrative work, throwing some part time work in Tydus’s direction from time to time. He has clumsy typing skills but is a great companion during those difficult working moments. If she ever needs a break, she knows that Tydus is there for a great big hug. But that’s not all…
There’s no better time of day for Tydus than when Yumna comes home. He cannot hold back his excitement everytime she walks through the door. All he can do is jump for joy until she embraces him with a necessary hug. They are a match made in heaven and he misses her dearly when she leaves to go out. Besides his beautiful looks, his large personality warms Yumna’s heart every day.
For newly minted pet owners, it can be hard to imagine just how much a new furry family member can change your life, but for Yumna, she now couldn’t imagine life without Tydus, as large as he has grown. Of course, he’s not the only Alaskan Malamute to have garnered an incredible social media following. Another of his ultra furry brethren, known as Loki the Wolfdog is a Malamute husky mix who has an impressive 1.7 million followers tuning in to his Instagram updates.
While Tydus might not have been the first giant dog ever adopted as a puppy, his internet exposure may have inspired others to share pictures of their own furry friends for others to enjoy. While photos abound of big dogs in unusual places, a regular favorite is seeing them happily curled up next to their owners, which often serves to highlight their vast frames. One Reddit user shared a picture of him being nearly absorbed by fur, saying it might be time for a larger couch.
Two’s A Crowd
One often marvels at those intrepid dog walkers who are hooked to multiple large dogs, all of whom desire to explore the world in different directions. For this Alaskan Malamute owner, it seems even two of the glorious beasts are difficult to manage on their daily walks. Here he struggles to rein them as their combined size massively overwhelms his own slender frame. These two fluff balls look utterly content with their location, however, and are only planning to move if bribed.
King Of The Castle
When this dog was brought home as a small pup, his owners, similar to Yumna, couldn’t have known just how much space their pooch would one day take up. As their love for him grew, so did his body, until it became clear who was really running things around here. Though he would have liked a slightly larger throne, this dog seems to think that there’s nothing out of the ordinary about this scene, even if he is nearly as big as the couch.
While training your impressionable dog, there are many manuals and instructional videos one can turn to for advice on how to go about such a task. Most professionals likely wouldn’t recommend the approach taken below, as this furry husky settles down for his afternoon lie down with a text book on how to fetch at his nose. Then again, if these owners have taught their dog how to read, they may know something more about dog training than the rest of us.
There are a few reasons dog owners opt for a smaller rather than larger dog, only one of which is space. When you’re looking at your adorable fluffer however, it can be hard sometimes not to pick them up and attempt to smother than in an embrace. When you’re the owner of a a fairly large Alaskan Malamute, however, you may be more at risk than your fur baby for being smothered. This bear sized pup looks pretty content with this human hug, for the time being.
Watching The Cub
Though Alaskan Malamutes are known for being a fairly active breed of dog, especially given that their size would require them to have large amounts of space at their paws should they truly want to run around, Eve has learned to mellow out around the cubs. Baby Adam might only be four months old here, but he was certainly well protected by his loving guard dog who seems to think of the baby as a pup of her own.
There’s little more memorable than your first joy ride, as this small baby is clearly experience in this picture. Though the term usually pertains to teenagers who take their parents’ car without permission, in this case, it seems there was at least one parental unit who consented to setting their baby on this terrifying course. This tot may looked wide eyed now, but hopefully she was more exhilarated than terrified. Only time will tell whether this experiment was worth it or not.
The may call dogs man’s best friend, but the truth is, there is little more heartwarming than watching a child grow up alongside a dog. Their dogs can serve as a protector, especially when they’re as large as this Alaskan Malamute, but also serve as a friend they turn to in times of need. Kids might have trouble expressing themselves verbally, but dogs can usually understand anyway. The dog below clearly knows just how much his family loves him, and will happily take all their hugs.
Entering Alaskan Territory
Given that Alaska is the biggest state in America, it’s only natural that such a large breed of dog would have developed out in the Northwestern wilderness. As Anna Svenska would discover, however, she didn’t have to leave the confines of civilization in order to find a whole pack of Alaskan Malamutes. By traveling mere hours by car, she was able to reach Arctic Rainbow Malamutes, where Lorna Bartlett cares for an impressive 12 dogs, all from the same massive breed.
Pulled From The Brink
Another veritable social media star is this enormous Alaskan Malamute, Danny, who is safely living his days in a doggie wonder within the borders of Canada after a daring rescue from Singapore. With Danny’s thick fur and direwolf like stature, it seems he is much better suited to the great wilderness afforded by the terrain of Canada. Danny not only presents his adorable antics to the world in various photos and videos, but his loving mommy also shares advice for caring for his breed.
Taming Of The Woldf
One of the best known big pups to take on the internet has to be Loki. His human dad, Kelly Lund, had been aching for a dog of his own after breaking away from his own pack. He instantly fell in love with the tiny ball of fur, and figured he had the expertise to appropriately train a highly active breed. Loki may look like a simple husky, but he actually has a mix of Alaskan Malamute and wolf in his genes.
A Virtual Album
Like most new parents, Lund couldn’t help but document every moment of Loki’s childhood and adolescence. The pictures he was sharing on his social media sites documenting Loki’s growth and milestones proved to be extremely popular. Who couldn’t help but coo over the incredible moments the two shared day in and day out? As Lund became aware of just how popular his puppy posts proved, he decided to move them over to an account of their own
North Of The Wall
Like the famed direwolves of Game of Thrones, Loki made for a striking figure against a backdrop of ice in his native Colorado. Pictures like these showing the full range of the dog’s adventures proved to be a hit with Instagram users, and Lund’s followers soared into the thousands. As the dog became ever more popular, brands began to take notice, and hoped that the pup could pull influence, like many of Instagram’s most popular human accounts.
Lund had never tried his hand at photography prior to adopting Loki, but he loved his fur baby so much, he just wanted to show the world just how special he was. Though he never actively tried to accrue followers on his Instagram account, the striking images he crafted with Loki caused users to stop and take notice. After all, it’s hard to ignore a pup like this appear to drive a car the way Loki is in the picture below.
On Top Of The World
With over 1.7 million Instagram followers, it could have been easy for Lund to get lost in the superficiality of social media. In his core, however, he knew the page’s success hinged on him to continue to focus his energy on his furry companion. The biggest step he’s taken outside of letting Loki be the animal that he is, was opening an online shop to sell some Loki themed memorabilia, from mugs to shirts, calendars, and more.
When asked about the adoption, Yumna only had positive things to say: “I fell in love the second I held him”, she shared with The Dodo. When the two first met, the puppy was only two weeks old, and since the first moment they locked eyes, Yumna and her puppy became inseparable. Because the dog was so small, he needed all the attention and nurturing he could get. According to Yumna, her heart melted on the spot.